This handbook, directed at medical professionals and students who are involved in developing the space industry or are academicians doing research in this area, covers current pharmaceutical knowledge about the difference in medication efficacy in space versus on Earth and includes trial results and best practices for the space research and travel industry. The well-known contributors come from an interdisciplinary background and address all aspects of the subject, from the physiological impact of spaceflight to the effects of radiation. As the commercial space industry expands its operations in industry and tourism, the field of space pharmaceuticals is growing commensurately. Existing pharmacological research from space is thoroughly covered in this book, and Earth applications are also described. Potential pharmacological solutions are posed along with the known challenges and examples from existing studies, which are detailed at length. This major reference work is a comprehensive and important medical resource for all space industry players.

Dr. Yashwant V. Pathak has over 13 years of versatile administrative experience in an Institution of Higher Education as Dean (and over 30 years as faculty and as a researcher in higher education after his Ph.D.) and now holds the position for Associate Dean for Faculty Affairs and tenured Professor of Pharmaceutical Sciences. Dr. Pathak is an internationally recognized scholar, researcher, and educator in the areas of healthcare education, nanotechnology, drug delivery systems, and nutraceuticals. His major achievements from 2015 to 2020 in international area include: 1. Fulbright Senior Scholar Core Fellowship Award 2015-2016 for Indonesia (visiting Ubaya University, Surabaya, Indonesia, from January till July 2017)2. Endeavour Executive Fellowship by Australian Government in 2015 in collaboration with Deakin University to work on siRNA delivery3. Prometeo Fellowship award from Ecuador Government, 20154. CNPQ Brazil Government Fellowship, visiting PUCRS in Porto Alegre every year for one month from 2015 till 2017 working on space pharmaceuticals and microgravity impact on stability of drug delivery systems5. Outstanding Achievement Award for Global Engagement by the University of South Florida, a unique award given to only one faculty/administrator annually6. Fellow of NSF I-Corps USF 20167. Outstanding Faculty Award from USF March 20178. Fulbright Specialist Fellowship 2019 for South Africa9. Outstanding Faculty Award from the University of South Florida 202010. Elected as fellow of American Association for the Advancement of Sciences (FAAAS) in 2021He has published extensively with over 50 edited volumes in the area of nanotechnology, drug delivery systems, artificial neural networks, conflict management, and cultural studies. Elsevier, John Wiley and Sons, Springer, Taylor and Francis, and many other international publishers publish his books. He has published over 300 research papers, reviews, and chapters in the books and presented in many national and international conferences. He is also actively involved in many nonprofit organizations, to mention a few, Hindu Swayamsevak Sangh, USA, Sewa International USA, International Accreditation Council for Dharma Schools and Colleges, International Commission for Human Rights and Religious Freedom, and many more. Dr. Marlise Araújo dos Santos holds a degree in Pharmacy from the Federal University of Rio Grande do Sul (1988), a Master's in Pharmacy from the Federal University of Rio Grande do Sul (1993) and a Ph.D. in Drug Delivery and Absorption where she worked in development of formulating a nasal formulation for Space Motion Sickness and a system to assess the permeability of drugs in cells grown in simulated microgravity - Kings College London University of London (2006). She coordinated the Joan Vernikos Aerospace Pharmacy Laboratory at PUCRS for 10 years. She has 21 years of research experience in Aerospace Pharmacy, working mainly on the following topics: simulated hypergravity, simulated microgravity, involving cell culture, drug synthesis, medicinal plants and pharmaceutical technology (nanotechnology). She is the Board of Advisor Member for Aerospace Pharmacy and Telepharmacy at the British company InnovaSpace Space without Borders (https://www.innovaspace.org/). She holds 3 patents in the area, author of several scientific articles and two international awards. She gives lectures and courses in the Aerospace Pharmacy area at universities and conferences in different countries (India, Portugal, Trinidad Tobago, United States, Italy, Poland, Germany, Turkey, Romania). She is a member of the Space 4 Women international group, part of the Space & Extreme Environment Research Center at UFCSPA (https://spacecenterufcspa.org/). She is a volunteer evaluator for NASA postdoctoral projects in the area of Space Life Science. She is a Member of the International

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