The present volume contains papers presented on the occasion of the Ichthyological Symposium on Genetics and Mutagenesis held on October 13 through 15, 1972 at the Biology Institute of the Association for Radia­ tion and Environmental Research in Neuherberg near Munich, Germany. These symposia have been held annually since 1955 by former students of Prof. C. Kosswig and Prof. F. Anders in Hamburg or Giessen. In the last two years attendance has increased beyond the national German basis, but the Neuherberg meeting of fish geneticists was the first that could be called "international", the participants coming from twelve different countries. The organization of this meeting was made possible by the support of the Association for Radiation and Environmental Research, which provided the financial backing; special thanks are due to Min.­ Rat. H. Costa and Dr. R. Wittenzellner. The scientific advice and encouragement of the Director of the Biology Institute, Prof. O. Hug, was also much appreciated, as was the helpful assistance of Dr. B. Betz and Dr. K. Gottel. In addition, I have to thank my colleagues and co­ workers Mdmes. E. Neubner, I.S. Otten, and K. Peters, Messrs. M. Murr and M. Wiestner, and Dr. S. Holzberg for their help in organizing the meeting. Apart from the papers presented at the above symposium, we have in­ cluded some papers by colleagues who were unable to attend the meeting.

Inhaltsangabe1. Historical Review.- The Role of Fish in Research on Genetics and Evolution.- 2. Sex-Determination and Melanoma Formation.- The Sex-Determining Mechanism of the Platyfish, Xiphophorus maculatus.- Preliminary Report on Sex Differentiation in Germ Cells of Normal and Transplanted Gonads in the Fish, Oryzias latipes.- Regulation of Gene Expression in the Gordon-Kosswig Melanoma System.- I. The Distribution of the Controlling Genes in the Genome of the Xiphophorin Fish, Platypoecilus maculatus and Platypoecilus variatus.- II. The Arrangement of Chromatophore Determining Loci and Regulating Elements in the Sex Chromosomes of Xiphophorin Fish, Platypoecilus maculatus and Platypoecilus variatus.- 3. Mutagenesis.- Radiation Damage in Fish.- Dominant Lethal Mutation Rates in the Fish, Oryzias latipes, Irradiated at Various Stages of Gametogenesis.- Chromosome Manipulation in Fish.- Teleosts as a Tool in Mutation Research.- 4. Chromosomes and Cytology.- Chromosomes of Two Fish-Species of the Genus Diretmus (Osteichthyes, Beryciformes: Diretmidae).- The Chromosomes of Some African Anuran Species.- Incorporation of H3-Thymidine into the DNA of Melanotic and Amelanotic Melanoma Expiants after Whole-Body X-Irradiation of Melanoma-Bearing Platyfish-Swordtail Hybrids.- Fate of Bacterial DNA Injected into Embryos of Poeciliid Fish.- Regulation of the Pigment Cell Arrangements in Species and Interspecies Hybrids of Xiphophorus (Pisces, Poeciliidae) by Cellular Interactions on the Fish Body.- Experimentally Induced Sexual Maturity in Artificially Reared Male Eels (Anguilla anguilla).- 5. Ethology.- Change of Aggressive Readiness in Post-Irradiation Generations of the Convict Cichlid Fish, Cichlasoma nigrofasciatum.- Attraction and Sexual Cycle of Poeciliids.- 6. Evolution.- Genetic Problems in the Regressive Evolution of Cavernicolous Fish.- Phylogenetic Age and Degree of Reduction of Cave Animals.- Origin and Synthesis of a Unisexual Fish.- Fish and Nature's Extensive Experiments with Gene Duplication.- 7. Biochemistry.- Biochemical Polymorphism and Microevolution Processes in Fish.- Developmental and Biochemical Genetics of Lactate Dehydrogenase Isozymes in Fishes.- Biochemical Evolution in the Genus Xiphophorus (Poeciliidae, Teleostei).- Tissue-Specific Preferential Expression of the Xiphophorus xiphidium Allele for 6-Phosphogluconate Dehydrogenase in Interspecific Hybrids of Platyfish (Poeciliidae, Teleostei).- Investigations on the Serum Polymorphism of Trout and Carp.- Inheritance of the S-Form of NADP-Dependent Isocitrate Dehydrogenase Polymorphism in Rainbow Trout.- Biochemical Variants in Pacific Salmon and Rainbow Trout: Their Inheritance and Application in Population Studies.

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