This book explores the mechanism of alkali-metal ion/molecule association reaction, surveys the instrumental basis to study its kinetic, and describes the instrumentation to the measurement of alkali-metal ion affinities. The applications of the ion complexation mechanism in the condensed phase in reaction to direct analysis MS are also covered. Other topics include mechanism and reaction rate, experimental and theoretical ion affinities, applications of ion attachment reactions (IAR) to mass spectrometry such as alkali ion CIMS, ion attachment MS and cationization mass spectrometry of ESI, FAB, FD, LD, MALDI and SIMS and topics of IAR-based direct analysis mass spectrometry.

Toshihiro Fujii received both his BSc and his PhD in inorganic chemistry from Kyoto University, Japan. In 1974, he joined the National Institute for Environmental Studies (Japan), where he was the Deputy Director of the Environmental Chemistry Division. He also was a Director Associate at Canon ANELVA Corporation, Visiting Professor at Tokyo Science University, at the University of Warwick (UK), at Ecole Normale Superiere (France) and Polytechnique (France) and Guest Professor at Tokyo Metropolitan University. From 2005, he worked at Meisei University as a Full Professor and he was in charge of Inorganic/Analytical Chemistry. He retired March 2012. He is now director associate at C& V Technix Co., Ltd.

1 Introduction.-2. Fundamentals of Ion Chemistry. -3 A theoretical Approach on ion-molecule complexation. -4 Experimental Methods and Instrumentation.-5 Applications of Association Reactions in the Gas .-6 Hybrid System with Ion Attachment Techniques.-7 Cationization mass spectrometry for condensed-phase samples.-8 Direct Analysis Mass Spectrometry.-9 Summary and perspectives.