InhaltsangabeI. Cannabinoid Receptor Ligands and Structure Activity Relationships Chapter 1. Structure Activity Relationships (SAR) of Classical Cannabinoids Raj K. Razdan Chapter 2. Endocannabinoids and Their Synthetic Analogs V. Kiran Vemuri and Alexandros Makriyannis Chapter 3. Cannabimimetic Indoles, Pyrroles and Indenes: Structure-Activity Relationships and Receptor Interactions John W. Huffman Chapter 4. Structure-Activity Relationships and Conformational Freedom of CB1 Receptor Antagonists and Inverse Agonists Yanan Zhang, Herbert H. Seltzman, Marcus Brackeen and Brian F. Thomas II. Cannabinoid Receptor Biology Chapter 5. Cannabinoid Receptor Genetics and Evolution Maurice R. Elphick and Michaela Egertová III. Cannabinoid Receptor Molecular Pharmacology Chapter 6. Cannabinoid Receptor Signal Transduction Pathways Emma Scotter, Scott Graham and Michelle Glass Chapter 7. Cannabinoid Agonist and Inverse Agonist Regulation of G-Protein Coupling Allyn C. Howlett, Lea W. Padgett and Joong-Youn Shim Chapter 8. Molecular Biology of Cannabinoid Receptors: Mutational Analyses of the CB receptors Mary E. Abood Chapter 9. Models of Cannabinoid Inverse Agonism, Neutral Antagonism and Agonism: Tools for Rational Drug Design Dow P. Hurst and Patricia H. Reggio IV. The Endocannabinoid System Chapter 10. Endocannabinoids as Modulators of Synaptic Signaling Sachin Patel and Cecilia J. Hillard Chapter 11. New Insights into the Endocannabinoid System by using Cannabinoid Receptor Knockout Mice Meliha Karsak, Itai Bab and Andreas Zimmer V. Cannabinoid Receptor Pharmacology Chapter 12. Preclinical Pharmacological and Brain Bioassay Systems for CB1 Cannabinoid Receptors Jenny L. Wiley and Billy R. Martin Chapter 13. Therapeutic Applications for Agents that Act at CB1 and CB2 Receptors Roger G. Pertwee and Adèle Thomas

I. Cannabinoid Receptor Ligands and Structure Activity Relationships Chapter 1. Structure Activity Relationships (SAR) of Classical Cannabinoids Raj K. Razdan Chapter 2. Endocannabinoids and Their Synthetic Analogs V. Kiran Vemuri and Alexandros Makriyannis Chapter 3. Cannabimimetic Indoles, Pyrroles and Indenes: Structure-Activity Relationships and Receptor Interactions John W. Huffman Chapter 4. Structure-Activity Relationships and Conformational Freedom of CB1 Receptor Antagonists and Inverse Agonists Yanan Zhang, Herbert H. Seltzman, Marcus Brackeen and Brian F. Thomas II. Cannabinoid Receptor Biology Chapter 5. Cannabinoid Receptor Genetics and Evolution Maurice R. Elphick and Michaela Egertova III. Cannabinoid Receptor Molecular Pharmacology Chapter 6. Cannabinoid Receptor Signal Transduction Pathways Emma Scotter, Scott Graham and Michelle Glass Chapter 7. Cannabinoid Agonist and Inverse Agonist Regulation of G-Protein Coupling Allyn C. Howlett, Lea W. Padgett and Joong-Youn Shim Chapter 8. Molecular Biology of Cannabinoid Receptors: Mutational Analyses of the CB receptors Mary E. Abood Chapter 9. Models of Cannabinoid Inverse Agonism, Neutral Antagonism and Agonism: Tools for Rational Drug Design Dow P. Hurst and Patricia H. Reggio IV. The Endocannabinoid System Chapter 10. Endocannabinoids as Modulators of Synaptic Signaling Sachin Patel and Cecilia J. Hillard Chapter 11. New Insights into the Endocannabinoid System by using Cannabinoid Receptor Knockout Mice Meliha Karsak, Itai Bab and Andreas Zimmer V. Cannabinoid Receptor Pharmacology Chapter 12. Preclinical Pharmacological and Brain Bioassay Systems for CB1 Cannabinoid Receptors Jenny L. Wiley and Billy R. Martin Chapter 13. Therapeutic Applications for Agents that Act at CB1 and CB2 Receptors Roger G. Pertwee and Adele Thomas

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