InhaltsangabeVOLUME 1: MOLECULAR BIOLOGY AND BIOCHEMISTRY Tuberculosis - Molecular Genetics and Biochemistry: Introduction Biochemistry of the Cell Wall Glycolipids and Polyketides of M. tuberculosis Physiology of M. tuberculosis Nutrient Transport Iron Uptake by M. tuberculosis Protein Transport PE and PPE Gene Family Members in M. tuberculosis Virulence/Persistence Mechanisms of M. tuberculosis Genomics Transcriptomics and Transcriptional Regulation Proteomics of M. tuberculosis Structure Molecular Mechanisms of Dormancy and Resuscitation M. tuberculosis in the Phagosome Molecular Mechanisms of Drug Resistance of M. tuberculosis Experimental Genetics of M. tuberculosis Molecular Evolution of Mycobacteria VOLUME 2: IMMUNOLOGY AND CELL BIOLOGY Introduction: Immunity to M. tuberculosis and BCG Recognition Receptors and Phagocytosis for M. tuberculosis Transcriptional Response of Macrophages and Dendritic Cells to M. tuberculosis Dendritic Cells and Antigen Presentation Killing Mechanisms of the Host Against M. tuberculosis Manipulation of the Macrophage Response Conventional T Cells and their Antigenic Repertoire Unconventional T Cells Cytokines in Tuberculosis Antibodies in Tuberculosis Pathology Maintenance of Latent Infection with Correlates of Protective Immunity Genetics of Resistance (mouse and man) HIV/TB Interactions Novel Vaccination Strategies Against Tuberculosis Experimental Animal Models of Tuberculosis VOLUME 3: CLINICS DIAGNOSTICS THERAPY AND EPIDEMIOLOGY Clinics Diagnostics Therapy Epidemiology: Introduction Global Epidemiology of Tuberculosis Surveillance Studies and Interpretation Molecular Epidemiology of M. tuberculosis Diagnosis of M. tuberculosis: Clinical Clinical Disease (with and without HIV) Management of Tuberculosis Patients Chemotherapy New Drugs and Clinical Drug Trials Latency Drug Resistance in Clinical Context Novel Drug Treatment Strategies - Co-infections Modeling BCG Vaccination

Prof. Dr. Stefan H.E. Kaufmann is Founding Director of the Max Planck Institute for Infection Biology, Berlin. He has published more than 600 scientific articles and is member of numerous scientific societies and committees e.g. current President of the European Federation of Immunological Societies, and Chair of the Immunology division of the American Society of Microbiology. He has won numerous prestigious awards including the Scientific Prize of Smith Kline Beecham and the Pettenkofer Prize. Paul van Helden is Professor of Medical Biochemistry at Stellenbosch University, South Africa. He is Director of Laboratory Research for the Desmond Tutu TB Centre. He is a past president of the SA Society of Biochemistry and Molecular Biology, and has received the Gold medal of this society. Eric Rubin is Professor of Immunology and Infectious Diseases at the Harvard School of Public Health. He carried out both his MD and PhD work at Tufts University. Warwick Britton is Professor of Medicine at the University of Sydney, Australia. He serves as Chairman of the State Committee for the Australian Society of Clinical Immunology and Allergy.

VOLUME 1: MOLECULAR BIOLOGY AND BIOCHEMISTRY Tuberculosis - Molecular Genetics and Biochemistry: Introduction Biochemistry of the Cell Wall Glycolipids and Polyketides of M. tuberculosis Physiology of M. tuberculosis Nutrient Transport Iron Uptake by M. tuberculosis Protein Transport PE and PPE Gene Family Members in M. tuberculosis Virulence/Persistence Mechanisms of M. tuberculosis Genomics Transcriptomics and Transcriptional Regulation Proteomics of M. tuberculosis Structure Molecular Mechanisms of Dormancy and Resuscitation M. tuberculosis in the Phagosome Molecular Mechanisms of Drug Resistance of M. tuberculosis Experimental Genetics of M. tuberculosis Molecular Evolution of Mycobacteria VOLUME 2: IMMUNOLOGY AND CELL BIOLOGY Introduction: Immunity to M. tuberculosis and BCG Recognition Receptors and Phagocytosis for M. tuberculosis Transcriptional Response of Macrophages and Dendritic Cells to M. tuberculosis Dendritic Cells and Antigen Presentation Killing Mechanisms of the Host Against M. tuberculosis Manipulation of the Macrophage Response Conventional T Cells and their Antigenic Repertoire Unconventional T Cells Cytokines in Tuberculosis Antibodies in Tuberculosis Pathology Maintenance of Latent Infection with Correlates of Protective Immunity Genetics of Resistance (mouse and man) HIV/TB Interactions Novel Vaccination Strategies Against Tuberculosis Experimental Animal Models of Tuberculosis VOLUME 3: CLINICS DIAGNOSTICS THERAPY AND EPIDEMIOLOGY Clinics Diagnostics Therapy Epidemiology: Introduction Global Epidemiology of Tuberculosis Surveillance Studies and Interpretation Molecular Epidemiology of M. tuberculosis Diagnosis of M. tuberculosis: Clinical Clinical Disease (with and without HIV) Management of Tuberculosis Patients Chemotherapy New Drugs and Clinical Drug Trials Latency Drug Resistance in Clinical Context Novel Drug Treatment Strategies - Co-infections Modeling BCG Vaccination

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