The Yearbook compiles the most recent developments in experimental and clinical research and practice in one comprehensive reference book. The chapters are written by well recognized experts in the field of intensive care and emergency medicine. It is addressed to everyone involved in internal medicine, anesthesia, surgery, pediatrics, intensive care and emergency medicine.

The Microcirculation.- The Microcirculation and Oxidative Stress.- Diagnosis and Treatment of the Septic Microcirculation.- Targeted Treatment of Microvascular Dysfunction.- Hemodynamic Monitoring.- Diagnosing Hypovolemia in Critically Ill Patients.- Measuring Stroke Volume Using Electrical Impedance Tomography.- Direct Arterial Pressure Monitoring: Pattern Recognition in the Management of Circulatory Failure.- Choosing Patient-tailored Hemodynamic Monitoring.- Resuscitation Issues.- Airway and Ventilation during CPR.- The Role of Gasping in Resuscitation.- Recent Concepts in Burn Resuscitation.- Intra-aortic Balloon Counterpulsation in Cardiogenic Shock.- Inflammatory Responses in the Lung.- Vascular Endothelial Growth Factor in Acute Lung Injury.- Role of CD14 in Lung Inflammation and Infection.- Mechanical Ventilation.- Measurement of Functional Residual Capacity during Mechanical Ventilation.- New and Conventional Strategies for Lung Recruitment in Acute Respiratory Distress Syndrome.- Consequences of Pleural Effusions for Respiratory Mechanics in Ventilated Patients.- Weaning Failure of Cardiac Origin: Recent Advances.- Respiratory Failure.- The Effects of Pleural Effusion.- Fluid Management in Acute Lung Injury and ARDS.- Life-threatening Respiratory Failure from H1N1 Influenza: Lessons from the Southern Cone Outbreak.- Infections.- Cytomegalovirus Infections in Non-immunocompromised Critically III Patients.- Prevention of Central Venous Catheter-related Infection in the Intensive Care Unit.- Standardization of Care to Improve Outcomes of Patients with Ventilator-associated Pneumonia and Severe Sepsis.- Strategies for Implementation of Evidence-based Guidelines for Prevention of Healthcare-associated Infection.- Antibiotic Stewardship: Possibilities when ResourcesAre Limited.- Metabolic Support.- Vitamin D in Critical Illness.- Anticoagulant Therapies.- Update on Antithrombin for the Treatment of Burn Trauma and Smoke Inhalation Injury.- Update on Physiological Anticoagulant Factor Concentrates in Patients with Sepsis.- Anemia and Blood Transfusions.- Venous Oxygen Saturation as a Physiologic Transfusion Trigger.- Tissue Protective Activities of Erythropoietin.- Renal Disease and Therapy.- Doppler-Based Renal Resistive Index: A Comprehensive Review.- Atrial Natriuretic Peptide in Postoperative Acute Renal Failure.- Renal Dysfunction in Chronic Liver Disease.- Hemofiltration and Hybrid Therapies in 2010.- Timing of Renal Replacement Therapy.- Neurological Aspects.- Multimodal Monitoring: A Critical Tool in the Neuro-ICU.- Hemodynamic Management of Acute Spinal Cord Injury.- Quantitative CT Scan and CT-Estimated Brain Specific Gravity in TBI.- Cerebral Perfusion in Sepsis.- Systemic Complications after Subarachnoid Hemorrhage.- Perioperative Management.- Epidural Anesthesia: New Indications for an Old Technique?.- Risk Assessment and Prevention of Perioperative Stroke.- Overview of Chronic Post-thoracotomy Pain: Etiology and Treatment.- Abdominal Compartment Syndrome.- The Polycompartment Syndrome: Whats all the Fuss About?.- Laparostomy: Why and When?.- Drug Distribution and Clearance.- Augmented Renal Clearance: Unraveling the Mystery of Elevated Antibiotic Clearance.- Drug Distribution: Is it a more Important Determinant of Drug Dosing than Clearance?.- Risk Stratification.- Risk Stratification in Severe Sepsis: Organ Failure Scores, PIRO or Both?.- Critical Care Outreach.- On the Response to Acutely Deteriorating Patients.- Identifying Cardiorespiratory Insufficiency Outside the ICU.- End-of-life Issues.- An Update on ICUManagement of the Potential Organ Donor.- End-of-life Care in the ICU: Commonalities and Differences between North America and Europe.- Patient Care.- Do Sleep Disorders have an Impact on Outcome in ICU Patients?.- Communication in Crisis: The Importance of Verbal Dexterity.- Patient Safety and Acute Care Medicine: Lessons for the Future, Insights from the Past.