This Recent Results in Cancer Research volume provides an up-to-date overview of the multidisciplinary management of locally confined rectal cancer as well as colorectal cancer with synchronous resectable liver metastases. The contents comprise the majority of the invited contributions from the Second St. Gallen EORTC Gastrointestinal Cancer Conference, held on 6-8 March 2014 in St. Gallen, Switzerland. Written by some of the worlds leading experts in the imaging, endoscopy, pathology, molecular biology, surgery, radiotherapy and medical oncology of rectal cancer and liver metastases, the chapters offer a comprehensive view on the latest recommendations in diagnosis and multidisciplinary treatment. Every clinician involved in the care of patients with rectal cancer will find this book interesting and helpful.

Introduction.- Epidemiology of colorectal cancer: risk factors, genetic predisposition.- Staging of Rectal Cancer Early Cancer Emerging issues in biology of colorectal cancer: Surgical Treatment of Rectal Cancer I.- Combined Modality Therapy in Rectal Cancer.- Surgical Treatment of Rectal Cancer II.- Issues in Combined Modality Treatment for Rectal Cancer. Emerging imaging techniques and radiological interventions for liver metastases: Rectal Cancer with Synchronous Liver Metastases I.- Rectal Cancer with Synchronous Liver Metastases II.