This book presents the state of the art in clinical plasma medicine and outlines translational research strategies. Written by an international group of authors, it is divided into four parts. Part I is a detailed introduction and includes basic and recent research information on plasma sciences, plasma devices and mechanisms of biological plasma effects. Parts II and III provide valuable clinical insights f.e. into the treatment of superficial contaminations, ulcerations, wounds, treatment of cells in cancer, special indications like in heart surgery, dentistry, palliative treatment in head and neck cancer or the use of plasma in hygiene. Part IV offers information on how and where to qualify in plasma medicine and which companies produce and supply medical devices and is thus of particular interest to medical practitioners.

This comprehensive book offers a sciences based practical to the clinical use of plasma and includes an extended selection of scientific medical data and translational literature.

HansRobert Metelmann (M.D., D.M.D., Ph.D.) is professor and head of the Department of Oral and Maxillofacial Surgery/Plastic Surgery at Greifswald University Medicine, Greifswald, Germany. He trained at the Cancer Therapy and Research Center at the University of Texas at San Antonio, USA. He is head of the National German Center of Plasma Medicine and coeditor of the journal Clinical Plasma Medicine.

Thomas von Woedtke (D.Sc., Ph.D.) is professor of Plasma Medicine at Greifswald University Medicine and program manager for Plasma Medicine at Leibniz Institute for Plasma Science and Technology (INP), Greifswald, Germany. He is coeditor of the journal Clinical Plasma Medicine and deputy head of the National German Center of Plasma Medicine.

KlausDieter Weltmann (D.Sc., Ph.D.) is chairman of the board of Leibniz Institute for Plasma Science and Technology and head of the Research Division Plasmas for Environment and Health. He held a profess

orship for Experimental Physics at Greifswald University and a visiting professorship at New York University. He is member of the board of the National German Center of Plasma Medicine.

Chapter I Understanding Physical Plasma Background and Principles1. Introduction to plasma medicine  2. Plasma sources for medical application 3. Low temperature plasma devices 4. Key roles of reactive oxygen and nitrogen species.-Chapter II Applying Physical Plasma Clinical Use1. Antimicrobial activity 2. Treatment of ulcerations 3. Treatment of wounds 4. Use in abdominal cancer 5. Palliative treatment of head and neck cancer 6. Treatment of split skin draft donor sites 7. Use in heart surgery 8. Application in hygiene.-Chapter III Investigating Physical Plasma New Horizons1. Side effect management 2. Perspectives in dental implantology 3. Perspectives in orthodontics4. Perspectives in dental caries 5. Perspectives in general surgery 6. Perspectives in aesthetic medicine 7. Perspectives in immunology 8. Enhancing skinpassing of drugs.-Chapter IV Practical Aspects1. Quality management by continuous medical education 2. Trainingwound nurses in plasma medicine  3. Plasma medical devices available on the market and based on comprehensive physical, biological, preclinical and clinical characterization: 3.1 kINPen MED, neoplas tools, Germany 3.2 PlasmaDerm, Cinogy, Germany 3.3 Canady Helios Cold Plasma Scalp, US Medical Innovations, USA 3.4 MicroPlaSter, ADTEC, UK.