InhaltsangabeI Growth Factors and Proto-Oncogenes in Development and Differentiation.- The Expression of Growth Factors and Growth Factor Receptors During Mouse Embryogenesis.- A Role for Proto-Oncogenes in Differentiation?.- Tissue-Specific Expression and Possible Functions of pp60c-src.- II Growth Factors, Receptors, and Related Oncogenes.- The Granulocyte-Macrophage Colony-Stimulating Factors.- Role of PDGF-Like Growth Factors in Autocrine Stimulation of Growth of Normal and Transformed Cells.- Transforming Growth Factor-?.- Transforming Growth Factor-?.- The Physiology of Epidermal Growth Factor.- Structural Relationships Between Growth Factor Precursors and Cell Surface Receptors.- Regulation of Cell Growth by the EGF Receptor.- Mutational Analysis of v-erbB Oncogene Function.- The c-fms Proto-Oncogene and the CSF-1 Receptor.- Activation of the c-src Gene.- Normal and Transforming N-Terminal Variants of c-abl.- Transformation by the v-abl Oncogene.- mos.- Structure and Function of the Human Interleukin-2 Receptor.- III Signal Transduction and ras Oncogenes.- Phosphorylation in Signal Transmission and Transformation.- Inositol Lipids and Cell Proliferation.- Protein Kinase C.- The Relevance of Protein Kinase C Activation, Glucose Transport, and ATP Generation in the Response of Haemopoietic Cells to Growth Factors.- Cytoplasmic pH and Free Ca2+ in the Action of Growth Factors.- Epidermal Growth-Factor Mediation of S6 Phosphorylation During the Mitogenic Response: A Novel S6 Kinase.- Role of G Proteins in Transmembrane Signaling: Possible Functional Homology with the ras Proteins.- The ras Gene Family.- RAS Genes and Growth Control in the Yeast Saccharomyces cerevisiae.- IV Gene Expression and Nuclear Oncogenes.- Regulation of Human Globin Gene Expression.- Regulation of Gene Expression by Steroid Hormones.- Enhancers as Control Elements for Tissue-Specific Transcription.- The Effect of DNA Methylation on DNA-Protein Interactions and on the Regulation of Gene Expression.- Trans-Acting Elements Encoded in Immediate Early Genes of DNA Tumor Viruses.- Transactivator Genes of HTLV-I, II, and III.- Involvement of Proto-Oncogenes in Growth Control: The Induction of c-fos and c-myc by Growth Factors.- Oncogenes and Interferons: Genetic Targets for Animal Cell Growth Factors.- Regulation of c-myc Expression in Normal and Transformed Mammalian Cells.- Properties of the myc and myb Gene Products.- The fos Oncogene and Transformation.- p53: Molecular Properties and Biological Activities.- V Malignant Transformation as a Multistep Process.- Oncogene Cooperativity in Stepwise Transformation of Rodent Embryo Fibroblasts by Polyoma Virus.- Role of the Middle T: pp60c-src Complex in Cellular Transformation by Polyoma Virus.- Oncogenes Cooperate, but How?.- Individual and Combined Effects of Viral Oncogenes in Hematopoietic Cells.- Multiple Factors Involved in B-Cell Tumorigenesis.- Molecular Events Associated with Tumor Initiation, Promotion, and Progression in Mouse Skin.- Amplification of Proto-Oncogenes and Tumor Progression.- Suppression of the Neoplastic Phenotype.- VI Oncogenesis in Transgenic Mice.- Oncogenesis in Transgenic Mice.