The present work aimed to study the efficacy of the drug Trayodashang Guggulu as single drug therapy & combination with Sahachar Taila Nasya as a combination therapy. For this 60 patients divided in two groups (each group 30) followed up upto 8 weeks. In statistical analysis the drug showed highly significant results in signs & symptoms of Manyagata vatavyadhi as- For Manyashool, the t value proved to be 10.42 & 15.24 in Group 1 & Group 2 respectively (p<0.001). For Manyagraha 6.49 & 10.41 in Group 1 & 2 respectively (p<0.001). For Bhrama it is 6.15 & 7.39 in Group 1 &2 respectively (p<0.001) & t29 for Mansabalakshaya is 5.75 & 8.22- Group 1 & 2 respectively (p<0.001), for 29 This research work finally concludes that the Trayodashang Guggul & Sahachar taila possesses a potent vatghna action with significant action on Manyashool & other symptoms. It is better effective, safe in Manyagatavata vyadhi patients.

Dr. Harsha Rathod obtained her Master's Degree from Mumbai University, India in 2007. Since She is practicing ayurveda especially Panchakarma Therapy in Pune, Maharashtra, India.

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