Actinidic archaea has been related to human diseases especially metabolic syndrome (Type 2 Diabetes, Coronary Artery Disease, Cerebral Vascular Disease, Hypertension and Dyslipidemia. The growth of endosymbiotic actinidic archaea leads to neanderthalisation of the human mind-body system. Neanderthal metabolonomics has been described in metabolic syndrome especially the Warburg phenotype and hyperdigoxinemia. Digoxin produced by archaeal cholesterol catabolism produces neanderthalisation. Prefrontal cortical atrophy and cerebellar hyperplasia has been related to metabolic syndrome. This leads on to dysautonomia with sympathetic hyperactivity and parasympathetic neuropathy in metabolic syndrome. A method to modulate archaeal symbiosis and interconverting homo sapien to homo neanderthalis and vice versa is described. This is done by a high fibre versus a low fibre diet, administration of antioxidant antibiotic and colonic microflora from human and cow dung. This can be called as a therapeutic archaeal symbiotic modulated human evolution for the treatment of metabolic syndrome.

Dr Ravikumar Kurup is the Director of the Metabolic Disorders Research Centre, Trivandrum. His areas of interest are Metabolic Medicine and Symbiotic Biology.