The major proportion of the world ecosystem is made up of human population. Human activities in the era of industrialization lead to global warming, accumulation of greenhouse gases and initiation of climate change. This leads to increase colonic and endosymbiotic archaeal growth generating methane which accelerates global warming which assumes a tempo of its own. The human diet in the modern era with low dietary fibre and increased fat and protein also leads to colonic and endosymbiotic archaeal growth. Modern civilization results in stress in societies leading to increased activation of the HPA axis leading to increased secretion of stress hormones, breeching of the gut blood barrier and leads to increase in archaeal growth and colonic archaeal translocation into the blood and tissues producing archaeal endosymbiosis. This leads to frontal cortical atrophy and cerebellar dominance. There is an endemic cerebellar cognitive affective disorder and disease phenotype. Climate change and its effects can be reversed by reduction in archaeal endosymbiosis induced by higher population dietary fibre intake and yoga. This constitutes symbiotic functional metabolic medicine.

Dr Ravikumar Kurup is the Director of the Metabolic Disorders Research Centre, Trivandrum. His areas of interest include Cognitive Neurology, Climatology and Neuroanthropology.