The use of analytical sciences in the discovery, development and manufacture of pharmaceuticals is wide-ranging. From the analysis of minute amounts of complex biological materials to the quality control of the final dosage form, the use of analytical technology covers an immense range of techniques and disciplines.
This book concentrates on the analytical aspects of drug development and manufacture, focusing on the analysis of the active ingredient or drug substance. It provides those joining the industry or other areas of pharmaceutical research with a source of reference to a broad range of techniques and their applications, allowing them to choose the most appropriate analytical technique for a particular purpose.
The volume is directed at analytical chemists, industrial pharmacists, organic chemists, pharmaceutical chemists and biochemists.
1. Quality control and regulation.
Clive Moores, Tunbridge Wells, UK.
2. Development of achiral separation methods in pharmaceutical analysis.
George Okafo and John K. Roberts, GlaxoSmithKline, Harlow, UK.
3. Chiral analysis of pharmaceuticals.
W. John Lough, University of Sunderland, UK.
4. Nuclear magnetic resonance spectroscopy in pharmaceutical analysis.
Richard J. Smith and Andrew J. Edwards, GlaxoSmithKline, Harlow, UK.
5. Mass spectrometry in pharmaceutical analysis.
Neville Haskins, Hampshire, UK.
6. Vibrational spectroscopy in pharmaceutical analysis.
Clare L. Anderton, GlaxoSmithKline, Harlow, UK.
7. Solid-state analysis and polymorphism.
Professor Dr Ulrich Griesser, University of Innsbruck, Austria and Dr Joseph G. Stowell, Purdue University, West Lafayette, Indiana, USA.
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8. Microscopy and imaging in pharmaceutical analysis.
Robert A. Carlton, Elan Pharmaceuticals, Pennsylvania, UK.
9. Process analysis in the pharmaceutical industry.
Martin Warman and Steve Hammond, Pfizer Ltd, Sandwich, UK.
References.
Index
