The chemistry of reactive intermediates is central to a modern mechanistic and quantitative understanding of organic chemistry. Moreover, it underlies a significant portion of modern synthetic chemistry and is integral to a molecular view of biological chemistry.Reviews in Reactive Intermediate Chemistry presents an up-to-date, authoritative guide to this fundamental topic. Although it follows Reactive Intermediate Chemistry by the same authors, it serves as a free-standing resource for the entire chemical and biochemical community.

The book includes:

Relevant, practical applicationsCoverage of such topics as mass spectrometry methods, reactive intermediates in interstellar medium, quantum mechanical tunnelling, solvent effects, reactive intermediates in biochemical processes, and excited state surfacesDiscussions of emerging areas, particularly those involving dynamics and theoriesConcluding sections identifying key directions for future research are provided at the end of each chapter

Matthew S. Platz, PhD, is Distinguished University Professor at The Ohio State University, with more than 200 research articles and more than a dozen patents to his credit. Dr. Platz has been an Alfred P. Sloan Fellow, Camille and Henry Dreyfus Teacher-Scholar, and a Cope Scholar of the American Chemical Society.

Robert A. Moss, PhD, is the Louis P. Hammett Professor of Chemistry at Rutgers, The State University of New Jersey. Dr. Moss has been an Alfred P. Sloan Fellow and has published 400 articles in the areas of reactive intermediates and chemistry in molecular aggregates.

Maitland Jones Jr., PhD, is David B. Jones Professor of Chemistry at Princeton University. He has published a textbook on organic chemistry and more than 200 papers focusing on the chemistry of reactive intermediates. He has also been an Alfred P. Sloan Fellow.

PREFACE.

CONTRIBUTORS.

PART 1 REACTIVE INTERMEDIATES.

1. Tetrahedral Intermediates Derived from Carbonyl Compounds, Pentacoordinate Intermediates Derived from Phosphoryl and Sulfonyl Compounds, and Concerted Paths Which Avoid Them (J.P. Guthrie).

2. Silicon-, Germanium-, and Tin-Centered Cations, Radicals, and Anions (V.Y. Lee and A. Sekiguchi).

PART 2 METHODS AND APPLICATIONS.

3. An Introduction to Time-Resolved Resonance Raman Spectroscopy and Its Application to Reactive Intermediates (D.L. Phillips, W.M. Kwok, and C. Ma).

4. Time-Resolved Infrared (TRIR) Studies of Organic Reactive Intermediates (J.P. Toscano).

5. Studies of the Thermochemical Properties of Reactive Intermediates by Mass Spectrometric Methods (P.G. Wenthold).

6. Reactive Intermediates in Combustion (J.K. Merle and C.M. Hadad).

7. Reactive Intermediates in Crystals: Form and Function (L.M. Campos and M.A. Garcia-Garibay).

8. The Chemical Reactions of DNA Damage and Degradation (K.S. Gates).

9. Conical Intersection Species as Reactive Intermediates (M.J. Bearpark and M.A. Robb).

10. Quantum Mechanical Tunneling in Organic Reactive Intermediates (R.S. Sheridan).

INDEX.